Fenasteride for Hair Loss
People who used Finasteride as a medication would have known of it primarily as a treatment for an enlarged prostate gland, also known as the Benign Prostatic Hyperplasia (BPH), to which it is popularly used as treatment for in line with other kinds of medications which works synergistically with it.
However, given Finasteride’s known power towards the inhibition of Dihydrotestosterone (DHT), a chemical in the body known to be responsible in promoting Baldness to both Men and Women, the same medication is also used as a treatment for Hair Loss.
As Men are known to contain more DHT in their bodies than Women, Finasteride works best by targeting this certain chemical in the body which, by nature, women may only have some of but nonetheless cause them their losses of hairs.
This question then arises: Does Finasteride work as good in Women as they do with Men?
Signs of Hair Loss
Although many Men and some Women do suffer Hair Loss, how the condition show its symptoms are not necessarily uniform for both Men and Women. In fact, how Men lose their Hair vary significantly than Women were they to experienced them.
Specifically about Androgenetic Alopecia, Men who experienced this condition tend to have a concentrated Loss of Hair at the top of the head which may start out as thinning of Hair at first but soon progress to a concentrated losses of Hair Strands.
Women, on the other hand, show signs of Androgenetic Alopecia by having a diffuse thinning of hair at the central part of the head with the frontal hairline preserved, if not accentuated.
While evidences are already strong that Testosterone and Dihydrotestosterone are to be blamed about men experiencing Baldness, the latter of which can be blocked to inhibit the severity of Hair Loss, the role of Androgen on women for Losing their Hair, on the other hand, still remains unclear.
Yet, for some reason, Women who suffer Female Pattern Baldness are being treated with Anti-Androgen therapy in line with other agents like the androgen receptor blockers but with only some success to women.
Finasteride as Treatment for Female Pattern Baldness
The use of Finasteride as a treatment for Female Pattern Baldness was at its biggest and earliest when it was conducted under clinical study with Post-Menopausal Women of normal serum testosterone at the age of around 41 to 60 as the subject.
With the subjects’ ages in relation to the severity of their Losing Hair as the factor, the test for the effectivity of Finasteride among the subjects were never found to be better than the placebo used under the same experiment based on actual results after 12 months of experiment despite the significant drop of serum dihydrotestosterone level among the subjects.
This lead the authors of the research to postulate that the effectivity of Finasteride as a treatment was severely hindered by the subjects’ hair thinning as a result of age.
However, positive effects were also produced among other Post-Menopaused subjects but at the expense of higher dosage administration of Finasteride and even longer treatment periods.
One good example of the positive effects of Finasteride to a subject was an old woman of 67 years of age with a record of progressing Hair Thinning but with no evidences of Hyperandrogenism.
The subject was intolerable of the anti-androgen therapy which makes use of both Spironolactone and Cyproterone.
However, after being amended to take Finasteride instead at 5 mg once a week for a full 12 months of study, positives result occurred as a result of the subject’s increased hair density and significant hair regrowth.
As one result is not enough to justify the effectivity of Finasteride as a Hair Loss Treatment among women, other significant subjects also showed similar positive reactions to the treatment regimen involving Finasteride after months of going through the experiment.
Broadening the scope of the study, 37 Pre-Menopausal Women who were experiencing Female Pattern Baldness were also added into the experiment but this time, a medication of Finasteride in line with Drosperinone-Containing Oral Contraceptives. Showing positive results, twenty-nine out of thirty-seven reported an improvement of their condition.
In fact, there are other more significant results coming from this same experiment containing both Pre- and Post-Menopausal Women as subjects.
Despite positive results on many subjects on the right conditions, there are still subjects who fail to react positively with Finasteride which gives the experiment yet an unclear and controversial result.
According to the study, the following are the key points that arose from it:
- Which type of subjects respond positively to the therapy is still unclear
- The optimal dosing for Women also remains obscure
- Higher dosage than their male counterparts may deem to be necessary
- Treatments require at least 6 months continuously in order for the effect to be sustained
- Women of child-bearing age are discouraged to the use of Finasteride; otherwise must use an effective contraceptive with the medication
Before deciding to make Finasteride as part of your Hair Growth Treatment Plan, it is best to consult a Physician first to avoid undesirable effects.